25.7.07

Asthma Studies

For the analysis of any clinical trial on asthma inhalers, your efficacy parameters are most probably going to be related to the spirometry measures and will almost always include the following
FEV1 - Forced expiratory volume in 1 second
The FEV1 is the volume exhaled during the first second of a forced expiratory maneuver started from the level of total lung capacity.

PEF - Peak expiratory flow
Expiratory peak flow (PEF) is the maximum flow generated during expiration performed with maximal force and started after a full inspiration .

FVC - Forced expiratory vital capacity
The volume change of the lung between a full inspiration to total lung capacity and a maximal expiration to residual volume. Here are more details on Spirometry. Also check out GINA for more Asthma information

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